Christian Seelos


My Publications

Cells treated with oxidized low-density lipoprotein activate a suicide mechanism (Apoptosis). Signs of Apoptosis include fragmentation of DNA in the cell’s nucleus (light areas). Seelos (1997).

Analytical model of the joint venture of Telenor and Grameen. We model business models to identify and make explicit the key organizational mechanisms that generate or fail to generate achievement of strategic objectives. (Seelos 2007, 2013).

1. Exner, M., Hermann, M., Hofbauer, R., Kapiotis, S., Speiser, W., Held, I., Seelos, Ch. and Gmeiner, B.M. (2000) The salicylate metabolite gentisic acid, but not the parent drug, inhibits glucose autoxidation-mediated atherogenic modification of low density lipoprotein. FEBS Lett. 470, 47-50

2. Hermann, M., Kapiotis, S., Hofbauer, R., Exner, M., Seelos, Ch., Held, I., Gmeiner, B. (1999) Salicylate inhibits LDL oxidation initiated by superoxide/nitric oxide radicals. FEBS Lett. 445, 212-214

3. Dallinger, G., Oberkofler, H., Seelos, Ch., Patsch, W. (1999) Transcriptional elongation of the rat apolipoprotein A-I gene: identification and mapping of two arrest sites and their signals. J. Lipid Res. 40, 1229-1239

4. Hermann, M., Kapiotis, S., Hofbauer, R., Seelos, Ch., Held, I., Gmeiner, B. (1999) Salicylate promotes myeloperoxidase-initiated LDL oxidation: Antagonization by its metabolite gentisic acid. Free Radical Biol. Med. 26, 1254-1260

5. Gerner, C., Seelos, Ch., Sauermann, G. (1998) Alteration of nuclear matrix protein composition during apoptosis in rat embryo cells. Exp. Cell. Res. 238, 472-480

6. Peck-Radosavljevic, M., Pidlich, J., Bergmann, M., Ferenci, P., Riegler-Keil, M., Seelos, Ch. et al. (1998) Preoperative TMM-classification is a better prognostic indicator for recurrence of hepatocellular carcinoma after liver transplantation than albumin mRNA in peripheral blood. J. Hepatol. 28, 497-503

7. Austen, M., Cerni, C., Henriksson, M., Hilfenhaus, S., Lüscher-Firzlaff, J. M., Menkel, A., Seelos, Ch., Sommer, A., Lüscher B. (1997) Regulation of cell growth by the Myc-Max-Mad network: Role of Mad proteins and YY1. Curr. Top. Microbiol. Immunol. 224, 123-130

8. Seelos, Ch., Gmeiner, B., Kapiotis, S., Cerni, Ch. (1997) Programmed death of endothelial cells triggered by oxidized low-density-lipoprotein. Biochem. Mol. Biol. Int. 42, 1015-1022

9. Kapiotis, S., Herrmann, M., Held, I., Seelos, Ch., Ehringer, H., Gmeiner, B. (1997) Genistein, the dietary-derived angiotensin inhibitor, prevents LDL oxidation and protects endothelial cells from damage by atherogenic LDL. Atheroscl. Thromb. Vasc. Biol. 17, 2868-2874

10. Kapiotis, S., Senguelge, G., Herrmann, M., Held, I., Seelos, Ch., Gmeiner, B. (1997) Paracetamol catalyzes myeloperoxidase-initiated lipid oxidation in LDL. Atheroscl. Thromb. Vasc. Biol. 17, 2855-2860

11. Seelos, Ch. (1997) A critical parameter determining the aging of DNA-calcium phosphate precipitates. Anal. Biochem. 245, 109-111

12. Gmeiner, B., Seelos, Ch. (1996) Tyrosine phosphorylation blocks tyrosine free radical formation and hence the hormonogenic iodination reaction. Free Radical Bio. Med. 21, 349-351

13. Cerni, Ch., Seelos, Ch. (1995) Papillomaviruses as promoting agents in human epithelial tumors. in: DNA Tumor Viruses: Oncogenic mechanisms. (Giuseppe Barbanti-Brodano et al., eds.), Plenum Press, New York, pp. 123-155

14. Gmeiner, B.M.K., Seelos, Ch. (1995) Modulation of biological tyrosine reactions by tyrosine phosphorylation. Wien. Klin. Wochenschr. 107, 687-689

15. Gmeiner, B., Seelos, Ch. (1995) Measurement of phosphotyrosine phosphatase activity using the Folin-Ciocalteu phenol reaction. Biochem. Mol. Biol. Int. 36, 943-948

16. Gmeiner, B., Leibl, H., Zerlauth, G., Seelos, Ch. (1995) Affinity binding of distinct functional fibronectin domains to immobilized metal chelates. Arch. Biochem. Biophys. 321, 40-47

17. Cerni, C., Bousset, K., Seelos, Ch., Burkhardt, H., Henriksson, M., Lüscher, B. (1995) Differential effects by Mad and Max on transformation by cellular and viral oncoproteins. Oncogene 11, 587-596

18. Soyal, S.M., Seelos, Ch., Lin-Lee, Y.C., Sanders, S., Gotto, A.M., Hachey, D.L., Patsch, W. (1995) Thyroid hormone influences the maturation of apolipoprotein A-I messenger RNA in rat liver. J. Biol. Chem. 270, 3996-4004

19. Seelos, Ch., Cerni, C. (1994) The addition of a nuclear matrix associated region promotes the biological effects of HPV11. Cell Biol. Int. 18, 388a

20. Gmeiner, B., Seelos, Ch. (1994) Nonreaction of phosphotyrosine with the Folin phenol reagent. Anal. Chem. 66, 917-918

21. Seelos, Ch., Gmeiner, B., Rainer, P., Marian, B. (1992) Dityrosine formation is impaired by tyrosine phosphorylation. Biochem. Biophys. Res. Comm. 188, 252-256

22. Radosavljevic, M., LinLee, Y.C., Soyal, S.M., Strobl, W., Seelos, Ch., Gotto, A.M., Patsch, W. (1992) Effect of sucrose diet on expression of apolipoprotein genes A-I, C-III and A-IV in rat liver. Atherosclerosis 95, 147-156

23. Jäger, W., Czejka, M., Seelos, Ch., Schüller, J., Fogl, U. (1991) Untersuchungen zur Zerfallskinetik von Ftorafur. Sci. Pharm. 59, 101-106

24. Goldenberg, H., Seelos, Ch., Chatwani, S., Chegini, S., Pumm, R. (1991) Uptake and endocytic pathway of transferrin and iron in perfused rat liver. Biochim. Biophys. Acta 1067, 145-152

25. Seelos, Ch., Hüttinger, M. (1990) Concerted response of low density lipoprotein receptor expression to ethinyl-estradiol or high-cholesterol diet in organs and white blood cells (WBC). Arteriosclerosis 10, 860a

26. Goldenberg, H., Seelos, Ch., Chegini, S., Chatwani, S. (1990) Endocytosis of transferrin and iron in perfused rat liver. Cell Biol. Int. Rep. 14, 242a

27. Gmeiner, B., Scheidel, H., Seelos, Ch., Vetterlein, M., Hüttinger, M., Zerlauth, G. (1990) Zinc ions increase tumor promoter binding to human lung fibroblasts but decrease tumor promoter-mediated fibronectin release. J. Cancer Res. Clin. Oncol. 116, 100a

28. Seelos, Ch. (1990) Cellular mechanisms regulating blood cholesterol levels. Effects of diet and hormones. Thesis, University of Vienna, Faculty of Natural Sciences.

29. Gmeiner, B., Seelos, Ch. (1989) Phosphorylation of tyrosine prevents dityrosine formation in vitro. FEBS Lett. 255, 395-397

30. Gmeiner, B.M.K., Seelos, Ch. (1989) Phosphatidylserine modulates calf intestine alkaline phosphatase activity towards low and high molecular weight substrate. Biochem. Int. 18, 767-773

31. Hüttinger, M., Gmeiner, B., Kraupp, M., Seelos, Ch., Kramar, R. (1989) Peroxisomal ß-oxidation and bile acid synthesis. J. Clin. Chem. Clin. Biochem. 27, 294-295

a) Journal Articles, Book Series, and selected Working Papers

(underlined= downloadable)

Mair, J., Wolf, M., Seelos, Ch. (2016) Scaffolding: A Process of Transforming Patterns of Inequality in Small-Scale Societies. The Academy of Management Journal, (forthcoming)

Seelos, Ch., Mair, J. (2016) When Innovation Goes Wrong. Stanford Social Innovation Review 14 (4), 27-33.

Sarker, A., Abed, S., Seelos, Ch. (2016) Lessons in Scaling and Failing: The challenges of scaling up programs aimed at empowering adolescent girls in Bangladesh and Uganda. Stanford Social Innovation Review 14 (2), Supplement, 14-15.

Seelos, Ch., Mair, J. (2014) Organizational Closure Competencies and Scaling: A Realist Approach to Theorizing Social Enterprise, in Jeremy Short (ed.) Social Entrepreneurship and Research Methods (Research Methodology in Strategy and Management, Volume 9), Emerald Group Publishing Limited, 147-188.

Seelos, Ch. (2014) Theorizing and Strategizing with Models: Generative Models of Social Enterprises. International Journal of Entrepreneurial Venturing 6(1), 6-21.

Seelos, Ch., Mair. J. (2013) Innovate and Scale: A Tough Balancing Act. Stanford Social Innovation Review 11(3), 12-14.

Seelos, Ch., Mair. J. (2012) Innovation is not the Holy Grail. Stanford Social Innovation Review 10, 44-49.

Seelos, Ch., Mair. J. (2012) What determines the capacity for continuous innovation in social sector organizations? PACS Report to the Rockefeller Foundation.

Seelos, Ch., Mair. J. (2012) Organizational Capacity for Continuous Innovation-Outline of a Research Agenda. PACS Report to the Rockefeller Foundation.

Seelos, Ch., Mair, J. (2011) Organizational Mechanisms of Inclusive Growth: A Critical Realist Perspective on Scaling. PACS Working Paper DI-0840-E (submitted).

Seelos, Ch., Mair, J., Battilana, J., Dacin, M.T, (2011) The embeddedness of social entrepreneurship: Understanding variation across geographic communities. Research in the Sociology of Organizations 33, 333-363.

Seelos, Ch. (2009) Waste Concern: A Multistakeholder Business Model Creating an Urban-Rural Symbiosis. IBWE Working Paper 05/2009.

Seelos, Ch. (2008) The unfinished business of economic development. Wanted: New Solutions. ICFAI Effective Executive (November), 32-35.

Seelos, Ch., Mair, J. (2007) Profitable business models and market creation in the context of deep poverty: A Strategic View. Academy of Management Perspectives 21, 49-63.

Paper won two international awards:

1.Best Paper for Practitioner Implications Award 2007 of the Strategic Management Society.

2.International Finance Corporation(IFC)/Financial Times (FT) 2008 Gold Price out of 750 submissions of the "private sector development" research essay competition.

Seelos, Ch., Mair, J. (2006) Sustainable development. How social entrepreneurs make it happen. IESE Working Paper.

Mair, J., Seelos, Ch. (2006) Digital Democracy. European Business Forum 26, 59-61.

Seelos, Ch., Mair, J. (2006) Social Entrepreneurs - The contribution of individual entrepreneurs to sustainable development. The ICFAI Journal for Entrepreneurship Development (March), 30-46.

Seelos, Ch., Mair, J. (2006) A strategic view on profitable business models and market creation in the context of deep poverty. IESE Working Paper.

Seelos, Ch., Mair, J. (2006) Sustainable development: how social entrepreneurs make it happen. IESE Working Paper.

Seelos, Ch., Mair, J. (2005) Social Entrepreneurship: Creating New Business Models to Serve the Poor. Business Horizons 48, 247-252.

Paper consistently ranked amongst “25 Hottest Articles” by Science Direct for this journal.

Seelos, Ch., Mair, J. (2005) Sustainable development, sustainable profits. European Business Forum 20, 49-53.

Mair, J., Seelos, Ch., Borwankar, A. (2005) Social entrepreneurial initiatives within the sustainable development landscape. International Journal of Entrepreneurship Education 2, 46-49.

Seelos, Ch. (2004) Finding a path in the sustainability jungle - a framework for corporate action. IESE Working paper.

Mair, J., Seelos, Ch., Borwankar, A. (2004) Emprendedores socials y desarrollo sostenible. Iniciativa Emprendedoria 43, 7-13.

Seelos, Ch. (1999) Lessons from Iraq on bioweapons. Nature 398, 187-188.

b) Book Chapters:

Seelos, Ch. (2009) New Models for the Future, in Managing in a Downturn: Leading Business Thinkers on How to Grow When Markets Don't, FT Prentice Hall, 133-137.

Seelos, Ch. (2009) De toekomst is aan het symbiotische model, in Solman, P. Mattu, R. (eds.) Mastering Management in crisistijd, Nederlandstalig.  

Seelos, Ch., Mair, J. (2009) Hope for Sustainable Development: How Social Entrepreneurs Make it Happen, in Ziegler, R. (ed.) An Introduction to Social Entrepreneurship: Voices, Preconditions and Contexts, Cheltenham: Edward Elgar, 228-245.

Seelos, Ch. (2008) The social responsibility of corporations is innovation, in Business and Poverty, Innovative Strategies for Global CSR, Vienna: ICEP/CODESPA, 65-69.

Seelos, Ch., Mair, J. (2007) How social entrepreneurs enable human, social, and economic development, in Rangan, V., Quelch, J., Herrero, G., and Barton, B. (eds.) Business Solutions for the Global Poor: Creating Social and Economic Value, San Francisco: Jossey-Bass, 271-278.

Seelos, Ch., Mair, J. (2006) The Sekem Initiative, in Improving Management. A Selection of the best Cases from IESE Business School (IESE), 269-297.

Mair, J., Seelos, Ch. (2006) The Sekem Initiative: a holistic vision to develop people, in F. Perrini (ed.) New Social Entrepreneurship: What awaits social entrepreneurship ventures? Edgar Elgar: Cheltenham, 210-223.

Seelos, Ch., Ganly, K., Mair, J. (2006) Social entrepreneurs directly contribute to global development goals, in Mair, J., Robinson, J., and Hockerts, K. (eds.) Social Entrepreneurship, Palgrave Macmillan.

c) Selected Newspaper Articles:

Seelos, Ch. (2010) El estrés del agua: las nuevas dimensiones de riesgo empresarial. Portafolio (Colombia) 1 Nov 2010.

Seelos, Ch. (2009) Managing in a downturn: New models for the future. Financial Times, Feb 13.  

Seelos, Ch. (2008) Company lessons in reaching the world’s poorest*. Financial Times, March 17 (*winning article of an essay competition sponsored by the Financial Times and the International Finance Corporation on the private sector's role in development).

Seelos, Ch. (2005) Social Entrepreneurs. Wirtschaftsblatt/CorporAID (October), 52.

Seelos, Ch. (2004) Strategisches Soziales Engagement. Wirtschaftsblatt/CorporAID 3-1, 70.

d) Case Studies:

Coudenhove-Kalergi, B., Seelos, Ch. (2012) EVN in Bulgaria (C) – Making it work… . Stanford PACS.

Coudenhove-Kalergi, B., Seelos, Ch. (2012) EVN in Bulgaria (B) – Engaging the Roma Community. Stanford PACS.

Seelos, Ch. (2011) EVN in Bulgaria - Eastern Phantasy Meets Eastern Reality. Case study. IESE Business School.

Seelos, Ch., Mair, J. (2007) Sekem – Liberating a Vision. An Artistic Approach to Entrepreneurship. Case study. IESE Business School.

Thurner, C., Seelos, Ch., Mair, J. (2006) Wasteconcern. IESE Study 33.

Seelos, Ch., Mair, J. (2006) BRAC: An enabling structure for social and economic development. IESE Study 34.

Seelos, Ch., Mair, J. (2004) Sekem - holistic development in the economic, cultural, and social spheres. Case study. IESE Business School.

Seelos, Ch., Mair, J. (2003) Entropy International - Enabling businesses to make a contribution to sustainable development. Case study. IESE Business School.

I. Natural Sciences

II. Social Sciences

New paper out at SSIR (Aug 2016):

When Innovation Goes Wrong